PDFs are available upon request.
*as corresponding author


Louisa J Stewart, YoungJin Hong, Isabel R Holmes, Samantha J Firth, Yasmin Ahmed, Janet Quinn, Yazmin Santos, Steven L Cobb, Nicholas S Jakubovics, Karrera Y Djoko*. (2023) Salivary Antimicrobial Peptide Histatin-5 Does Not Display Zn (II)-Dependent or-Independent Activity against Streptococci. ACS Infectious Diseases Articles ASAP. [LINK]

Atreyee Mishra, Karrera Y Djoko, Yi-Hsuan Lee, Rianne M Lord, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Sidharth Chopra, James W Walton. (2023) Water-soluble copper pyrithione complexes as therapeutic agents. Organic and Biomolecular Chemistry Advance Article. [LINK]

Caroline Donaghy, Jose Gabriel Javellana, YoungJin Hong, Karrera Y Djoko, Alfredo M Angeles-Boza. (2023) The Synergy between Zinc and Antimicrobial Peptides: An Insight into Unique Bioinorganic Interactions. Molecules 28(5), 2156. [LINK]


YoungJin Hong, Eilidh S Mackenzie, Samantha J Firth, Jack RF Bolton, Louisa J Stewart, Kevin J Waldron, Karrera Y Djoko*. (2022) Copper stress perturbs zinc and manganese homeostasis in Streptococcus pyogenes. bioRxiv. [LINK]

Charlotte I Z O’Hern and Karrera Y Djoko*. (2022) Copper cytotoxicity: cellular consequences of non-cognate coordination chemistry. mBio 13(3):e00434-22. [LINK]

Stephan Brouwer, Magnus Jespersen, Cheryl-lynn Y Ong, David De Oliveira, Bernhard Keller, Amanda Cork, Karrera Y Djoko, Mark R Davies, Mark J Walker. (2022) Streptococcus pyogenes hijacks host glutathione for growth and innate immune evasion. mBio 13(3):e0067622. [LINK]

Guillaume A Petit, Yaoqin Hong, Karrera Y Djoko, Andrew E. Whitten, Emily J Furlong, Airlie J McCoy, Jacqueline M. Gulbis, Makrina Totsika, Jennifer L Martin, Maria A Halili. (2022) The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity. Acta Crystallographica D78:337-352. [LINK]

Louisa J Stewart, YoungJin Hong, Isabel Holmes, Samantha Firth, Jack Bolton, Yazmin Santos, Steven Cobb, Nicholas Jakubovics, Karrera Y Djoko*. (2022) The role of metal binding in the function of the human salivary antimicrobial peptide histatin-5. bioRxiv. [LINK]


Louisa J Stewart, Cheryl-lynn Y Ong, May M Zhang, Stephan Brouwer, Liam McIntyre, Mark R Davies, Mark J Walker, Alastair G McEwan, Kevin J Waldron, Karrera Y Djoko*. (2020) Role for glutathione in buffering excess intracellular copper in Streptococcus pyogenes. mBio 11:e02804-20.  [LINK]


Andrew G Turner, Karrera Y Djoko, Y Ong Cheryl-lynn, Timothy C Barnett, Mark J Walker, Alastair G McEwan. (2019) Group A Streptococcus coordinates manganese import and iron efflux in response to hydrogen peroxide stress. Biochemical Journal 476(3):595-611.  [LINK]

Louisa J Stewart, Denis Thaqi, Bostjan Kobe, Alastair G McEwan, Kevin Waldron, Karrera Y Djoko*. (2019) Handling of nutrient copper in the bacterial envelope. Metallomics 11(1):50-63.  [LINK]


Karrera Y Djoko, Maud ES Achard, Minh-Duy Phan, Alvin W Lo, Manfredi Miraula, Sasiprapa Prombhul, Steven J Hancock, Kate M Peters, Hanna E Sidjabat, Patrick N Harris, Nataša Mitić, Timothy R Walsh, Gregory J Anderson, William M Shafer, David L Paterson, Gerhard Schenk, Alastair G McEwan, Mark A Schembri. (2018) Copper ions and coordination complexes as novel carbapenem adjuvants.  Antimicrobial Agents and Chemotherapy 62:e02280-17.  [LINK]  [PDF]


Karrera Y Djoko*, Minh-Duy Phan, Kate M Peters, Mark J Walker, Mark A Schembri, Alastair G McEwan. (2017) Interplay between tolerance mechanisms to copper and acid stress in Escherichia coli. Proceedings of the National Academy of Sciences 114(26): 6818-6823.   [LINK]   [PDF]

James W Marsh, Karrera Y Djoko, Alastair G McEwan, Wilhelmina M Huston. (2017) Copper(II)-bis(thiosemicarbazonato) complexes as anti-chlamydial agents. Pathogens and Disease 75(7): ftx084.   [LINK]   [PDF]

Andrew G Turner, Y Ong Cheryl-lynn, Karrera Y Djoko, Nicholas P West, Mark R Davies, Alastair G McEwan, Mark J Walker. (2017) The PerR-regulated P1B-4-Type ATPase (PmtA) acts as a ferrous iron efflux pump in Streptococcus pyogenes. Infection and Immunity 85(6): e00140-17.   [LINK]   [PDF]

Andrew G Turner, Y Ong Cheryl-lynn, Mark J Walker, Karrera Y Djoko, Alastair G McEwan. (2017) Transition metal homeostasis in Streptococcus pyogenes and Streptococcus pneumoniae. Advances in Microbial Physiology 70: 123-191.   [LINK]


Rafael M Couñago, Nathan H Chen, Chiung-Wen Chang, Karrera Y Djoko, Alastair G McEwan, Bostjan Kobe. (2016) Structural basis of thiol-based regulation of formaldehyde detoxification in Haemophilus influenzae by a MerR regulator with no sensor region. Nucleic Acids Research 44(14): 6981-6993.   [LINK]   [PDF]

Nathan H Chen, Karrera Y Djoko, Frédéric J Veyrier, Alastair G McEwan. (2016) Formaldehyde stress responses in bacterial pathogens. Frontiers in Microbiology 7.   [LINK]   [PDF]


Freda E-C Jen, Karrera Y Djoko, Stephen J Bent, Christopher J Day, Alastair G McEwan, Michael P Jennings. (2015) A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria. The FASEB Journal 29(9): 3828-3838.   [LINK]   [PDF]

Karrera Y Djoko*, Maira M Goytia, Paul S Donnelly, Mark A Schembri, William M Shafer, Alastair G McEwan. (2015) Copper(II)-bis(thiosemicarbazonato) complexes as antibacterial agents: Insights into their mode of action and potential as therapeutics. Antimicrobial Agents and Chemotherapy 59(10): 6444-6453.   [LINK]   [PDF]

Karrera Y Djoko, Cheryl-lynn Y Ong, Mark J Walker, Alastair G McEwan. (2015) The role of copper and zinc toxicity in innate immune defense against bacterial pathogens. Journal of Biological Chemistry 290(31): 18954-18961.   [LINK]   [PDF]


John M Atack, Ines Ibranovic, Cheryl-Lynn Y Ong, Karrera Y Djoko, Nathan H Chen, Rachel Vanden Hoven, Michael P Jennings, Jennifer L Edwards, Alastair G McEwan. (2014) A role for lactate dehydrogenases in the survival of Neisseria gonorrhoeae in human polymorphonuclear leukocytes and cervical epithelial cells. The Journal of Infectious Diseases 210(8): 1311-1318.   [LINK]   [PDF]

Karrera Y Djoko*, Brett M Paterson, Paul S Donnelly, Alastair G McEwan. (2014) Inhibition of respiratory Complex I by copper(II)-bis(thiosemicarbazonato) complexes. Metallomics 6(12): 2250-2259.   [LINK]

Karrera Y Djoko*, Brett M Paterson, Paul S Donnelly, Alastair G McEwan. (2014) Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action. Metallomics 6(4): 854-863.   [LINK]


Karrera Y Djoko* and Alastair G McEwan. (2013) Antimicrobial action of copper is amplified via inhibition of heme biosynthesis. ACS Chemical Biology 8(10): 2217-2223.   [LINK]

Nathan H Chen, Rafael M Counago, Karrera Y Djoko, Michael P Jennings, Michael A Apicella, Bostjan Kobe, Alastair G McEwan. (2013) A glutathione-dependent detoxification system is required for formaldehyde resistance and optimal survival of Neisseria meningitidis in biofilms. Antioxidants & Redox Signaling 18(7): 743-755.   [LINK]

Karrera Y Djoko, Maud ES Achard, Alastair G McEwan. (2013) Copper in immune cells. In Encyclopedia of Inorganic and Bioinorganic Chemistry. 1-11.

John M Atack, Yogitha N Srikhanta, Karrera Y Djoko, Jessica P Welch, Norain HM Hasri, Christopher T Steichen, Rachel N Vanden Hoven, Sean M Grimmond, Dk Seti Maimonah Pg Othman, Ulrike Kappler, Michael A Apicella, Michael P Jennings, Jennifer L Edwards, Alastair G McEwan. (2013) Characterization of an ntrX mutant of Neisseria gonorrhoeae reveals a response regulator that controls expression of respiratory enzymes in oxidase-positive Proteobacteria. Journal of Bacteriology 195(11): 2632-2641.   [LINK]   [PDF]


Karrera Y Djoko, Jessica A Franiek, Jennifer L Edwards, Megan L Falsetta, Stephen P Kidd, Adam J Potter, Nathan H Chen, Michael A Apicella, Michael P Jennings, Alastair G McEwan. (2012) Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress. Infection and Immunity 80(3): 1065-1071.   [LINK]   [PDF]


Stephen P Kidd, Karrera Y Djoko, JiaQi Ng, M Pilar Argente, Michael P Jennings, Alastair G McEwan. (2011) A novel nickel responsive MerR-like regulator, NimR, from Haemophilus influenzae. Metallomics 3(10): 1009-1018.   [LINK]

Alastair G McEwan, Karrera Y Djoko, Nathan H Chen, Rafael LM Couñago, Stephen P Kidd, Adam J Potter, Michael P Jennings. (2011) Novel bacterial MerR-Like regulators. In 58: 1-22.   [LINK]


Karrera Y Djoko, Lee Xin Chong, Anthony G Wedd, Zhiguang Xiao. (2010) Reaction mechanisms of the multicopper oxidase CueO from Escherichia coli support its functional role as a cuprous oxidase. Journal of the American Chemical Society 132(6): 2005-2015.   [LINK]

Before 2010

Karrera Y Djoko, Zhiguang Xiao, Anthony G Wedd. (2008) Copper resistance in Escherichia coli: The multicopper oxidase PcoA catalyzes oxidation of copper(I) in CuICuII‐PcoC. ChemBioChem 9(10): 1579-1582.   [LINK]

Simon C Drew, Karrera Y Djoko, Lianyi Zhang, Melissa Koay, John F Boas, John R Pilbrow, Zhiguang Xiao, Kevin J Barnham, Anthony G WeddG. (2008) Electron paramagnetic resonance characterization of the copper-resistance protein PcoC from Escherichia coli. Journal of Biological Inorganic Chemistry 13(6): 899-907.   [LINK]

Karrera Y Djoko, Zhiguang Xiao, David L Huffman, Anthony G Wedd. (2007) Conserved mechanism of copper binding and transfer. A comparison of the copper-resistance proteins PcoC from Escherichia coli and CopC from Pseudomonas syringae. Inorganic Chemistry 46(11): 4560-4568.   [LINK]

Marcus R Helfrich, Lauren K Mangeney-Slavin, M Scott Long, Karrera Y Djoko, Christine D Keating. (2002) Aqueous phase separation in giant vesicles. Journal of the American Chemical Society 124(45): 13374-13375.   [LINK]